Profluent

Profluent is an AI-first biotechnology company based in Berkeley, California, founded in 2022. The company specializes in advanced protein design using deep generative models and machine learning. Profluent combines artificial intelligence with traditional wet-lab techniques to create, optimize, and validate novel proteins that can outperform natural proteins in various applications, including human health, therapeutics, agriculture, and industrial enzymes. Their comprehensive protein design platform integrates AI-driven generative models with in-house validation, allowing for efficient and scalable protein engineering. Profluent's technology supports the design of various biomolecules, including enzymes, antibodies, and gene editors like OpenCRISPR, the first AI-designed gene editing tool. Their work has been validated through peer-reviewed research, showcasing the ability of their models to generate fully functional proteins comparable to those evolved naturally. Profluent aims to partner with biotechnology and pharmaceutical firms to co-develop innovative protein solutions, reflecting strong industry confidence from notable venture capital investors.