Prime Medicine

Prime Medicine, Inc. is a biotechnology company based in Cambridge, Massachusetts, dedicated to developing one-time curative genetic therapies through its proprietary Prime Editing technology. Founded in 2019, the company focuses on precisely correcting disease-causing genetic mutations at their exact locations in the genome, avoiding double-strand DNA breaks. The Prime Editing platform, likened to a "DNA word processor," allows for the targeted replacement of faulty DNA sequences, potentially addressing around 90% of known disease-causing mutations. Prime Medicine is actively developing therapies for various conditions, including genetic disorders and certain types of leukemia, and collaborates with organizations like Cimeio Therapeutics to enhance its therapeutic offerings. The company employs over 200 professionals and is led by CEO Allan Reine and co-founder Dr. Andrew Anzalone, who brings extensive expertise in gene editing research.

5 open jobs5 jobs
Research Cambridge, United States Founded 2019 ~215 employees NASDAQ: PRME

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Employees
215
-2.3% in the 3 months to Jun 2025
Revenue / employee
$194K
Revenue ~$41.6M
Stock
PRME
NASDAQ
12-month attrition
22.5%
Tech: 18.8%
H1B filings, FY2026
1
Sponsors visas
Open jobs
5
Last 30 days

Headcount trend

Prime Medicine went from 218 employees in Jul 2023 to 215 in Jun 2025. Jan to Jun 2025: 20 people joined, 10 left.

Headcount data through Jun 2025

Org structure

Headcount by department

Other170
Operations15
Engineering15
Finance6
Sales5
HR3
Marketing1

Hiring now

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Senior Director, BiometricsCambridge, MA $263k - $292k 2 weeks agoSenior Manager, Regulatory OperationsCambridge, MA $149k - $166k 2 weeks agoAssociate Scientist/Engineer II Technology, Development and Operations - ChemistryCambridge, MA $80k - $90k 2 weeks agoResearch Associate, Automation & AssaysCambridge, MA $72k - $80k 2 weeks agoVP, Regulatory AffairsCambridge, MA $313k - $348k 3 weeks ago

H-1B sponsorship

H-1B Sponsorship Limited
H-1B Filings by Department
Engineering13
Operations2
Historical LCA Filings
2026
1
2025
8
2024
6

The department split adds up all the years listed above. FY2026 alone: 1 filings.

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Prime Medicine FAQ

How many employees does Prime Medicine have?

Prime Medicine has about 215 employees, down 2.3% over the 3 months to Jun 2025.

Does Prime Medicine sponsor H1B visas?

Yes. Prime Medicine filed 1 H1B (LCA) application in FY2026, according to the latest U.S. Department of Labor disclosures. It was for a Engineering role.

What is Prime Medicine's revenue per employee?

Prime Medicine makes about $194K in revenue per employee, based on $41.62M annual revenue and 215 employees.

Is Prime Medicine a public company?

Yes. Prime Medicine is publicly traded under the ticker PRME on NASDAQ.

Data from Company Prospectus, DOL LCA disclosures, WARN notices and 6figr salary profiles.