Prime Medicine
Prime Medicine, Inc. is a biotechnology company based in Cambridge, Massachusetts, dedicated to developing one-time curative genetic therapies through its proprietary Prime Editing technology. Founded in 2019, the company focuses on precisely correcting disease-causing genetic mutations at their exact locations in the genome, avoiding double-strand DNA breaks. The Prime Editing platform, likened to a "DNA word processor," allows for the targeted replacement of faulty DNA sequences, potentially addressing around 90% of known disease-causing mutations. Prime Medicine is actively developing therapies for various conditions, including genetic disorders and certain types of leukemia, and collaborates with organizations like Cimeio Therapeutics to enhance its therapeutic offerings. The company employs over 200 professionals and is led by CEO Allan Reine and co-founder Dr. Andrew Anzalone, who brings extensive expertise in gene editing research.
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Headcount trend
Prime Medicine went from 252 employees in Oct 2024 to 184 in Sep 2026. Apr to Sep 2026: 12 people joined, 9 left.
Org structure
Headcount by department
H-1B sponsorship
The department split adds up all the years listed above. FY2026 alone: 1 filings.
Peer reviews
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Anonymous peer reviews on OffTheRecord
Hiring now
Base Salary:
$106k - $117k
Base Salary:
$295k - $312k
Base Salary:
$219k - $232k
Base Salary:
$360k - $408k
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Prime Medicine FAQ
How many employees does Prime Medicine have?
Prime Medicine has about 184 employees, up 4.5% over the 3 months to Sep 2026.
Does Prime Medicine sponsor H1B visas?
Yes. Prime Medicine filed 1 H1B (LCA) application in FY2026, according to the latest U.S. Department of Labor disclosures. It was for a Engineering role.
What is Prime Medicine's revenue per employee?
Prime Medicine makes about $226K in revenue per employee, based on $41.62M annual revenue and 184 employees.
Is Prime Medicine a public company?
Yes. Prime Medicine is publicly traded under the ticker PRME on NASDAQ.
Data from Company Prospectus, DOL LCA disclosures, WARN notices and 6figr salary profiles.
