Lyell Immunopharma

Lyell Immunopharma is a clinical-stage biotechnology company based in South San Francisco, California, with an additional office in Seattle, Washington. The company is dedicated to developing next-generation T-cell therapies aimed at treating solid tumors and hematologic malignancies. By integrating advanced research in T-cell biology with innovative engineering, Lyell seeks to create durable and curative therapies for cancer patients. Lyell's pipeline includes several promising candidates, such as LyL797, a CAR T-cell therapy for solid tumors, and LYL119, an investigational therapy for hematologic malignancies. The company employs technologies like T-cell reprogramming and epigenetic reprogramming to enhance T-cell persistence and prevent exhaustion, addressing challenges in cancer treatment. Led by experienced industry professionals, Lyell emphasizes collaborative partnerships and patient-centric innovation to advance its clinical programs and expand treatment options for refractory cancers.

Research South San Francisco, United States Founded 2018 ~180 employees NASDAQ: LYEL

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Employees
180
-1.1% in the 3 months to Jun 2025
Annual revenue
~$65K
Stock
LYEL
NASDAQ
12-month attrition
24.1%
Tech: 20.7%
H1B filings, FY2026
1
Sponsors visas
Open jobs
2
Last 30 days

Headcount trend

Lyell Immunopharma went from 248 employees in Jul 2023 to 180 in Jun 2025. Jan to Jun 2025: 5 people joined, 24 left.

Headcount data through Jun 2025

Org structure

Headcount by department

Other125
Operations24
Engineering12
Finance9
Sales5
Marketing3
HR2

Salaries at Lyell Immunopharma

All salaries

1 salary profiles in the US

Pay by level, gender and ethnicity

H-1B sponsorship

H-1B Sponsorship Limited
H-1B Filings by Department
Engineering2
Operations1

The department split adds up all the years listed above. FY2026 alone: 1 filings.

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Lyell Immunopharma FAQ

How many employees does Lyell Immunopharma have?

Lyell Immunopharma has about 180 employees, down 1.1% over the 3 months to Jun 2025.

Does Lyell Immunopharma sponsor H1B visas?

Yes. Lyell Immunopharma filed 1 H1B (LCA) application in FY2026, according to the latest U.S. Department of Labor disclosures. It was for a Operations role.

How much does Lyell Immunopharma pay?

6figr has 1 salary profile for Lyell Immunopharma in the US, with pay broken down by role, level, gender and ethnicity on the Lyell Immunopharma salaries page. See Lyell Immunopharma salaries

Is Lyell Immunopharma a public company?

Yes. Lyell Immunopharma is publicly traded under the ticker LYEL on NASDAQ.

Data from Company Prospectus, DOL LCA disclosures, WARN notices and 6figr salary profiles.